Isotopically Labeled Compounds
Medchemexpress LLC 1-Bromotridecane-d4 25mg
1-Bromotridecane-d4 is the deuterium labeled 1-Bromotridecane[1]
Medchemexpress LLC Crisaborole-d4 | 2268785-42-6 | 98.8% | 255.07 | 1 ML
Crisaborole-d4 is deuterium labeled Crisaborole, a potent inhibitor of PDE4 and cytokine release. It inhibits PDE4 with an IC50 of 0.49 μM. This compound is suitable for use as a tracer and an internal standard for quantitative analysis, leveraging the potential of deuteration to affect pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Potent inhibitor of PDE4 and cytokine release
- Suitable as a tracer
- Suitable as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories MALONIC ACID (2-13C, 99%), 0.5 G, 55514-11-9
MALONIC ACID (2-13C, 99%), 0.5 G, 55514-11-9
Cambridge Isotope Laboratories CHENODEOXYCHOLIC ACID (24-13C, 99%), 0.5 G, 52918-92-0
CHENODEOXYCHOLIC ACID (24-13C, 99%), 0.5 G, 52918-92-0
Medchemexpress LLC Uridine-13C,15N2 | 369656-75-7 | 1 MG
Uridine-13C,15N2 is a 13C- and 15N-labeled Uridine. It is intended for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules as tracers for quantitation during drug development. Deuteration has gained attention due to its potential to affect pharmacokinetic and metabolic profiles of drugs.
- Can be utilized as a tracer.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories DL-CYSTINE (3,3,3',3'-D4, 98%), 1 G
DL-CYSTINE (3,3,3',3'-D4, 98%), 1 G
Cambridge Isotope Laboratories L-GLUTAMIC ACID (3,4-13C2, 99%), 0.25 G
L-GLUTAMIC ACID (3,4-13C2, 99%), 0.25 G
Medchemexpress LLC L-Methionine-DL-sulfoximine | 15985-39-4 | 98.0% | 1 G
L-Methionine-DL-sulfoximine (MSX; MSO) is a highly specific and irreversible inhibitor of Glutamine synthetase (GS). It acts as a potent convulsant, primarily affecting astroglia metabolically and morphologically. This compound has been utilized to inhibit Gln-dependent ammonia-stimulated neuronal toxicity in vitro and significantly increases the release rate of fixed nitrogen in cyanobacteria. It is considered a promising candidate for research in biofertilizers and convulsive seizures (CS).
- Highly specific and irreversible inhibitor of glutamine synthetase.
- Potent convulsant affecting astroglia.
- Inhibits Gln-dependent ammonia-stimulated neuronal toxicity in vitro.
- Increases release rate of fixed nitrogen in cyanobacteria.
- Potential for research in biofertilizers and convulsive seizures.
Medchemexpress LLC Candesartan-d4 | 1346604-70-3 | 98.2% | 1 MG
Candesartan-d4 (CV-11974-d4) is the deuterium labeled Candesartan, an orally active angiotensin II AT1-Receptor blocker and PPAR-γ agonist. It has potent and long-lasting antihypertensive effects and is used for the research of hypertension, chronic heart failure (CHF), and traumatic brain injury (TBI).
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Phenacetin-d5 (Acetophenetidin-d5) | 69323-74-6 | MFCD04118296 | 99.5% | 184.25 g/mol | C10H8D5NO2 | 10 MG
Phenacetin-d5 is a deuterium-labeled analogue of phenacetin used as an analytical standard and internal standard in mass spectrometry and quantitative assays. Supplied as a 10 mg solid with high chemical and isotopic purity, it is suitable for method development, quantitative analysis, and pharmacokinetic studies.
- Deuterium-labeled internal standard for mass spectrometry.
- High analytical purity (>99.5%).
- Provided as a 10 mg solid suitable for reconstitution.
- Molecular weight 184.25 g/mol and formula C10H8D5NO2.
- Useful for quantitative assays and method validation.
Medchemexpress LLC Octanal-d16 | 1219794-66-7 | 10 MG
Octanal-d16 is the deuterium labeled Octanal, a fragrant aldehyde with antioxidant and antibacterial activity. It exhibits cytotoxicity towards HeLa cells with an IC50 value of 3.5 μg/mL. Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Cytosine-d2 | 106391-24-6 | MFCD01317453 | 99.7% | 113.11 g/mol | C4H3D2N3O | 10 MG
Cytosine-d2 is a deuterium-labeled isotopic standard of the nucleobase cytosine intended for analytical and biochemical applications, including mass spectrometry, tracer experiments, and method development. It is supplied as a dry solid and requires appropriate handling and storage.
- Deuterium-labeled cytosine (d2) for isotope dilution and tracer studies.
- Suitable as an internal standard for LC-MS and GC-MS quantification.
- High purity, approximately 99.7%.
- Soluble in DMSO at 10 mg/mL with ultrasonic and warming; hygroscopic DMSO may affect solubility.
- Store at 4°C protected from light; in solvent store at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Piperacillin-d5 | 61477-96-1 | 96.0% | 522.59 | C23H22D5N5O7S | 10 MG
Piperacillin-d5 is a deuterium-labeled (d5) analogue of the β-lactam antibiotic piperacillin supplied as a solid powder for use as an internal standard and tracer in quantitative analyses by NMR, GC-MS, and LC-MS. The d5 labeling enables mass-based discrimination with minimal alteration of chemical properties, making it suitable for pharmacokinetic and bioanalytical studies.
- Deuterium-labeled (d5) internal standard for quantitative analysis.
- Solid powder form for analytical sample preparation.
- Purity approximately 96.0%.
- Molecular weight 522.59 g/mol; formula C23H22D5N5O7S.
- Offered in small pack sizes for analytical workflows (for example, 10 mg).
Medchemexpress LLC Florfenicol-d3 | 2213400-85-0 | 99.9% | 5 MG
Florfenicol-d3 is the deuterium labeled form of Florfenicol, a veterinary antibiotic. It is used for bovine respiratory disease and in aquaculture to control enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g. This product is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.